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THBS1 / Thrombospondin-1

thrombospondin 1

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.

Gene Name: thrombospondin 1
Synonyms: THBS1, Thrombospondin-1, Thrombospondin-1p180, TSP, TSP1, THBS-1, THBS, Thrombospondin 1, TSP-1
Target Sequences: NM_003246 NP_003237.2 P07996

Publications (6)

1
Activation of the ROCK1 Branch of the Transforming Growth Factor-² Pathway Contributes to RAGE-Dependent Acceleration of Atherosclerosis in Diabetic ApoE-Null Mice. De-xiu Bu, Vivek Rai, Xiaoping Shen, Rosa Rosario, Yan Lu, Vivette D'Agati, Shi Fang Yan, Richard A. Friedman, Edem Nuglozeh and Ann Marie Schmidt. Circulation research. 2010 106:1040-51. (WB; Mouse) [Full Text Article] [PubMed:20133903] [PMC:PMC2848909]
2
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD. Nature communications. 2019 January;10:76. [Full Text Article] [PubMed:30622267] [PMC:PMC6325143] Related Antibodies: LS-B4155.
3
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P. Cell reports. 2019 September;28:3329-3337.e5. [Full Text Article] [PubMed:31553904] [PMC:PMC6907691]
4
Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts. Tyler A Smith, Cameron L Ghergherehchi, Haley O Tucker, George D Bittner. Journal of neuroinflammation. 2020 October;17:287. [Full Text Article] [PubMed:33008419] [PMC:PMC7532577] Related Antibodies: LS-C137099.
5
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity10<sup> Campus Moulin de la Housse, Plateau Technique Mobile en Cytométrie Environnementale MOBICYTE, UFR Sciences Exactes et Naturelles, Université de Reims Champagne-Ardenne/INERIS, 51000 Reims, France. Albin Jeanne , Thomas Sarazin , Magalie Charlé , Catherine Moali, Caroline Fichel, Camille Boulagnon-Rombi , Maïté Callewaert, Marie-Christine Andry, Eric Diesis, Frédéric Delolme , Damien Rioult, Stéphane Dedieu. Cancers. 2021 Oct;13:5019. [Full Text Article] [PubMed:34638503] [PMC:PMC8508526]
6
Thrombospondin-1 aggravates colonic mucosal inflammatory injuries via promoting the differentiation of CD11c+<sup> macrophages with lysosomal activity limited in colitis. Ping Tao, Beiping Zhang, Jiang Lin, Shiying Wang. Annals of translational medicine. 2021 December;9:1738. [Full Text Article] [PubMed:35071432] [PMC:PMC8743729]
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Products
ELISA Kits (27)
Custom (1)
Development Kit (1)
Sandwich (23)
Sandwich CLIA (2)
THBS1 / Thrombospondin-1 (27)
Human (10)
Mouse (8)
Rat (3)
Bovine (1)
Chicken (1)
Guinea pig (1)
Pig (1)
Rabbit (1)
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DevKit DuoPlus (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (6)
96-Well Strip Plate (19)
Antibody Pair and Standard (1)
No (26)
Yes (1)
Breast Milk (1)
Cell Culture Supernatants (4)
Cell Lysates (2)
Plasma (23)
Saliva (1)
Serum (15)
Tissue Homogenates (9)
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$715
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$782
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$749
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$779
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$764
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
1563 - 100000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$748
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
5.49 - 4000 pg/ml
Chemiluminescent
Plasma
1 Plate/$871
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
8.192 - 800 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Tissue Homogenates
1 Plate/$744
THBS1 / Thrombospondin-1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
400 - 25000 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$562
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
THBS1 / Thrombospondin-1 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
500 Wells/$1,062; 1000 Wells/$1,546
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$779
Viewing 1-25 of 27 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).