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THBD / CD141 / Thrombomodulin
thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
| Gene Name: | thrombomodulin |
| Synonyms: | THBD, BDCA3, CD141 antigen, CD141, AHUS6, Fetomodulin, THPH12, TM, THRM, Thrombomodulin |
| Target Sequences: | NM_000361 NP_000352.1 P07204 |
Publications (2)
1
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A +<sup> CD141 +<sup> cDC1 and CD14 +<sup> antigen-presenting cell recruitment. Bas D Koster #, Marta López González #, Mari Fcm van den Hout , Annelies W Turksma, Berbel Jr Sluijter, Barbara G Molenkamp, Paul Am van Leeuwen, Saskia Vosslamber, Rik J Scheper, Alfons Jm van den Eertwegh, M Petrousjka van den Tol, Ekaterina J Jordanova , Tanja D de Gruijl. Journal for immunotherapy of cancer. 2021 Mar;;9:e001962. [Full Text Article]
[PubMed:33737341]
[PMC:PMC7978250]
2
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Anjan K Bongoni, Nikolai Klymiuk, Eckhard Wolf, David Ayares, Robert Rieben, Peter J Cowan. Transplantation. 2016 September;100:1871-9. [Full Text Article]
[PubMed:27077599]
☰ Filters
Products
Proteins
(14)
Type
Recombinant
(14)
Target
THBD / CD141 / Thrombomodulin
(14)
Publications
No
(14)
Tag
6His, C-terminus
(1)
His
(5)
His, C-Terminal
(1)
His, N-Terminal
(1)
His,C-terminus
(2)
His-GST
(1)
His-T7
(1)
Species
Dog
(1)
Human
(6)
Mouse
(3)
Rabbit
(1)
Rat
(3)
Source
E. coli
(7)
HEK 293 Cells
(1)
Human
(2)
Human Cells
(1)
Mammalian Cells
(2)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(6)
Biologically Active
Biologically active
(2)
E. coli
His-T7
18.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
2 µg/$268; 10 µg/$349
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Human THBD / CD141 / Thrombomodulin Protein (Recombinant His, C-Terminal) (Ala19-Ser515) - LS-G55770
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
52.9kD
50 µg/$395; 500 µg/$1,585; 1 mg/$2,157; 10 µg/$277
None
Biologically active
10 µg/$476
Human THBD / CD141 / Thrombomodulin Protein (Recombinant His,C-terminus) (Ala19-Ser515) - LS-G139419
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.9 kDa
10 µg/$365; 50 µg/$479
E. coli
His, N-Terminal
10.7kDa
10 µg/$281; 50 µg/$442; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,521
E. coli
His-GST
53.5 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
55.2 kDa
50 µg/$854
Mouse THBD / CD141 / Thrombomodulin Protein (Recombinant His,C-terminus) (Leu17-Ser517) - LS-G140686
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.6 kDa
10 µg/$344; 50 µg/$584
E. coli
His
16.4 kDa
10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562
E. coli
His
18.6 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
16.4 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His
18.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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