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THBD / CD141 / Thrombomodulin
thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
| Gene Name: | thrombomodulin |
| Synonyms: | THBD, BDCA3, CD141 antigen, CD141, AHUS6, Fetomodulin, THPH12, TM, THRM, Thrombomodulin |
| Target Sequences: | NM_000361 NP_000352.1 P07204 |
Publications (2)
1
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A +<sup> CD141 +<sup> cDC1 and CD14 +<sup> antigen-presenting cell recruitment. Bas D Koster #, Marta López González #, Mari Fcm van den Hout , Annelies W Turksma, Berbel Jr Sluijter, Barbara G Molenkamp, Paul Am van Leeuwen, Saskia Vosslamber, Rik J Scheper, Alfons Jm van den Eertwegh, M Petrousjka van den Tol, Ekaterina J Jordanova , Tanja D de Gruijl. Journal for immunotherapy of cancer. 2021 Mar;;9:e001962. [Full Text Article]
[PubMed:33737341]
[PMC:PMC7978250]
2
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Anjan K Bongoni, Nikolai Klymiuk, Eckhard Wolf, David Ayares, Robert Rieben, Peter J Cowan. Transplantation. 2016 September;100:1871-9. [Full Text Article]
[PubMed:27077599]
☰ Filters
Products
ELISA Kits
(41)
Type
Competitive EIA
(2)
Custom
(4)
Sandwich
(31)
Sandwich CLIA
(4)
Target
THBD / CD141 / Thrombomodulin
(41)
Reactivity
Human
(10)
Mouse
(10)
Rat
(6)
Canine
(1)
Chicken
(1)
Dog
(3)
Guinea pig
(1)
Monkey
(1)
Pig
(3)
Porcine
(1)
Rabbit
(3)
Format
12 x 8-Well Microstrips
(3)
96-Well Microplate
(7)
96-Well Strip Plate
(31)
Publications
No
(41)
Sample Type
Cell Culture Supernatants
(4)
Cell Lysates
(1)
Plasma
(35)
Serum
(29)
Tissue Homogenates
(10)
Urine
(4)
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$699
Sandwich
96-Well Strip Plate
Pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$779
Sandwich
96-Well Strip Plate
Rat
93.75 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Microplate
Rat
93.75 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$659
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$582
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$699
Sandwich
96-Well Strip Plate
Human
46.88 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$764
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$715
Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$764
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$585
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich CLIA
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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