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TGM3 / Transglutaminase 3

transglutaminase 3

Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.

Gene Name: transglutaminase 3
Synonyms: TGM3, TGE, Transglutaminase 3, Transglutaminase E, Transglutaminase-3, TGase-3, TG(E), TGase E
Target Sequences: NM_003245 NP_003236.3 Q08188

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TGM3 / Transglutaminase 3 (6)
No (6)
6His, N-terminus (1)
His (1)
His-S (1)
Myc-DDK (Flag) (3)
Human (4)
Mouse (1)
293T Cells (1)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (2)
Low endotoxin level (1)
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Baculovirus
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
78.8 kDa
100 µg/$721
TGM3 / Transglutaminase 3 Protein - Recombinant Transglutaminase 3, Epidermal By SDS-PAGE
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E. coli
His
26.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
TGM3 / Transglutaminase 3 Protein - Purified recombinant protein TGM3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
76.5 kDa
20 µg/$1,107
TGM3 / Transglutaminase 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
76.5 kDa
20 µg/$215
TGM3 / Transglutaminase 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
76.5 kDa
100 µg/$710
TGM3 / Transglutaminase 3 Protein - Recombinant Transglutaminase 3, Epidermal By SDS-PAGE
Select
E. coli
His-S
32.0 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).