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Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
Gene Name: | transforming growth factor, beta receptor associated protein 1 |
Synonyms: | TGFBRAP1, TRAP-1 |
Target Sequences: | NM_004257 NP_004248.2 Q8WUH2 |
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