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6737 Mowry Ave
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TGFA / TGF Alpha
transforming growth factor, alpha
TGFA / TGF Alpha is a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | transforming growth factor, alpha |
| Family/Subfamily: | TGF beta , not assigned-TGF beta |
| Synonyms: | TGFA, Etgf, TFGA, TGF Alpha, Tgf type 1, TGF-alpha, Egf-like tgf |
| Target Sequences: | NM_003236 NP_003227.1 P01135 |
Publications (1)
1
Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Friedrich Felix Hoyer, Kamila Naxerova, Maximilian J Schloss, Maarten Hulsmans, Anil V Nair, Partha Dutta, David M Calcagno, Fanny Herisson, Atsushi Anzai, Yuan Sun, Gregory Wojtkiewicz, David Rohde, Vanessa Frodermann, Katrien Vandoorne, Gabriel Courties, Yoshiko Iwamoto, Christopher S Garris, David L Williams, Sylvie Breton, Dennis Brown, Michael Whalen, Peter Libby, Mikael J Pittet, Kevin R King, Ralph Weissleder, Filip K Swirski, Matthias Nahrendorf. Immunity. 2019 November;51:899-914.e7. [Full Text Article]
[PubMed:31732166]
[PMC:PMC6892583]
☰ Filters
Products
Proteins
(20)
Type
Over-Expression Lysate
(5)
Recombinant
(15)
Target
TGFA / TGF Alpha
(20)
Format
Animal-free
(1)
Publications
No
(20)
Tag
GST
(3)
GST, N-terminus
(1)
His, N-Terminal
(2)
His-S
(1)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Human
(14)
Rabbit
(1)
Rat
(1)
Sheep
(2)
Source
293T Cells
(3)
CHO Cells
(1)
E. coli
(10)
HEK 293 Cells
(2)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(6)
Biologically Active
Biologically active
(6)
Animal-free
Animal-free
(1)
E. coli
His-S
10.4 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
5.5 kDa
20 µg/$268; 100 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
20 µg/$282; 100 µg/$370
None
Biologically active
5.5 kD
0.1 mg/$484
Wheat Germ Extract
GST
43.23 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
16.8 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
16.8 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
16.8 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
16.8 kDa
100 µg/$494
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
5.8 kDa
1 mg/$1,263; 10 µg/$253; 50 µg/$304
HEK 293 Cells
Myc-DDK (Flag)
16.8 kDa
100 µg/$494
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~5.8 kDa
20 µg/$286
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 50 amino acid recombinant protein has a predicted molecular mass of approximately 5.5 kD. The DTT-reduced and non-reduced protein migrate at approximately 8 and 6 kD by SDS-PAGE respectively. The N-terminal amino acid is Val.
10 µg/$249; 25 µg/$276; 100 µg/$355
E. coli
His, N-Terminal
15kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
GST
35.33 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Yeast
GST
35.33 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
8-10 kDa (SDS-PAGE)
5 µg/$239; 25 µg/$262
E. coli
His-T7
11.8 kDa
10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107
E. coli
His, N-Terminal
9.5kDa
10 µg/$295; 50 µg/$530; 200 µg/$1,045; 100 µg/$847; 1 mg/$2,211; 500 µg/$1,728; 5 mg/$3,697; 2 mg/$2,402
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