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TFF3 / Trefoil Factor 3
trefoil factor 3 (intestinal)
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF3 is expressed in goblet cells of the intestines and colon. The TFF3 gene consists of 3 exons, with exon 2 encoding the trefoil domain. The TFF1, TFF2, and TFF3 genes are located within a 55 kb region, suggesting they evolved from a common ancestor by duplication.
| Gene Name: | trefoil factor 3 (intestinal) |
| Synonyms: | TFF3, HP1.B, Intestinal trefoil factor, HITF, ITF, TFI, p1B, Polypeptide P1.B, Trefoil factor 3, Trefoil factor 3 (intestinal) |
| Target Sequences: | NM_003226 |
Publications (2)
1
Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression. Zhu Y, Zhao S, Deng Y, Gordillo R, Ghaben AL, Shao M, Zhang F, Xu P, Li Y, Cao H, Zagnitko O, Scott DA, Gupta RK, Xing C, Zhang BB, Lin HV, Scherer PE. Diabetes. 2017 November;66:2789-2799. [Full Text Article]
[PubMed:28877911]
[PMC:PMC5652600]
2
A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity. Lei Chen, Natalie H Toke, Shirley Luo, Roshan P Vasoya, Robert L Fullem, Aditya Parthasarathy, Ansu O Perekatt, Michael P Verzi. Nature genetics. 2019 May;51:777-785. [Full Text Article]
[PubMed:30988513]
[PMC:PMC6650150]
Related Antibodies: LS-C662731.
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TFF3 / Trefoil Factor 3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Cancer Pathology
Cancer
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (3D9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$485
Cancer Pathology
Cancer
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
TFF3 / Trefoil Factor 3 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
Cancer Pathology
Cancer
TFF3 / Trefoil Factor 3 Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
TFF3 / Trefoil Factor 3 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Cancer Pathology
Cancer
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$485
TFF3 / Trefoil Factor 3 Rabbit anti-Pig Polyclonal (aa22-80) Antibody
Pig
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
TFF3 / Trefoil Factor 3 Rabbit anti-Dog Polyclonal (aa24-80) Antibody
Dog
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
TFF3 / Trefoil Factor 3 Rabbit anti-Dog Polyclonal (aa24-80) (Biotin) Antibody
Dog
WB
Biotin Conjugated
100 µl/$328; 200 µl/$378; 500 µl/$545; 1 ml/$645; 2 ml/$879; 5 ml/$1,464
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal (aa22-94) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (aa72-130) (OTI5B2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (aa72-130) (Carrier-free) (OTI5B2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (aa72-130) (OTI4D10) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (aa72-130) (Carrier-free) (OTI4D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TFF3 / Trefoil Factor 3 Mouse anti-Human Monoclonal (1D3G1) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$316; 100 µg/$386
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
TFF3 / Trefoil Factor 3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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product results
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