TFE3

transcription factor binding to IGHM enhancer 3

Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

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Products

ELISA Kits (2)

Type

DNA Binding (1)

Sandwich (1)

Target

TFE3 (2)

Reactivity

Human (2)

Mouse (1)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (1)

Publications

No (2)

Sample Type

Cell Lysates (1)

Nuclear Lysates (1)

Tissue Homogenates (1)

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Human TFE3 (Sandwich ELISA) ELISA Kit - LS-F9525

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

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Mouse/Human TFE3 (DNA-Binding ELISA) ELISA Kit - LS-F815

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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