TET2

tet methylcytosine dioxygenase 2

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.

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Products

Antibodies (21)

Type

Primary (21)

Target

TET2 (21)

Reactivity

Human (21)

Mouse (5)

Rat (2)

Application

IHC (8)

IHC-P (4)

WB (20)

ELISA (12)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (21)

Isotype

IgG (16)

Clonality

polyclonal pc (21)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (16)

Epitope

aa528-554 (7)

aa1-156 (2)

aa100-150 (1)

aa1833-2002 (1)

Publications

No (20)

Yes (1)

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TET2 Antibody LS-C334211

(4.1) Rating

(2) Publication(s)

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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TET2 Antibody (aa100-150) LS-C290887

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa100-150) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µg/$514

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TET2 Antibody (aa1833-2002) LS-C377947

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa1833-2002) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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TET2 Antibody LS-C336148

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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TET2 Antibody LS-C153760

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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TET2 Antibody LS-C660969

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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TET2 Antibody LS-C668553

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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TET2 Antibody LS-C802598

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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TET2 Antibody LS-C341814

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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TET2 Antibody LS-C771119

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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TET2 Antibody (aa528-554) LS-C325670

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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TET2 Antibody (aa528-554, Biotin) LS-C224300

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TET2 Antibody (aa528-554, FITC) LS-C224304

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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TET2 Antibody (aa528-554, PE) LS-C224301

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

TET2 Antibody (aa528-554, Azide-free, HRP) LS-C224302

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

TET2 Antibody (aa528-554, APC) LS-C224298

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

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TET2 Antibody (aa1-156) LS-C744616

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa1-156) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

25 µl/$304

Select

TET2 Antibody (aa1-156) LS-C744617

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa1-156) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$567

Select

TET2 Antibody LS-C409077

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

Select

TET2 Antibody (aa528-554) LS-C157167

Antibody:

TET2 Rabbit anti-Human Polyclonal (aa528-554) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TET2 Antibody LS-C331509

Antibody:

TET2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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