TERT / Telomerase

telomerase reverse transcriptase

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.

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Products

ELISA Kits (33)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (2)

Custom (1)

Sandwich (26)

Sandwich CLIA (2)

Target

TERT / Telomerase (33)

Reactivity

Human (9)

Mouse (5)

Rat (5)

Bovine (1)

Chicken (2)

Dog (1)

Guinea pig (2)

Monkey (2)

Porcine (2)

Rabbit (2)

Sheep (2)

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Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (26)

Publications

No (33)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (18)

Serum (18)

Tissue Homogenates (5)

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Human TERT / Telomerase (Cell-Based ELISA) ELISA Kit - LS-F2346

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F7351

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12713

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F34958

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12716

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Dog TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12715

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F9171

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

Select

Rat TERT / Telomerase (Competitive EIA) ELISA Kit - LS-F28088

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

250 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Porcine TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48392

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F24090

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human TERT / Telomerase (CLIA) ELISA Kit - LS-F29534

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F49248

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human Phospho-TERT / Telomerase (Ser824) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1428

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Bovine TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12714

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Rat TERT / Telomerase (Custom ELISA) ELISA Kit - LS-F19329

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F20864

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F20980

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F34955

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse TERT / Telomerase (Competitive EIA) ELISA Kit - LS-F28951

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Chicken TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48389

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48390

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Guinea pig TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48391

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48393

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48394

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

Select

Chicken TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F48399

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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