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TCF4

transcription factor 4

TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box (&#039E-box&#039) binding site (&#039CANNTG&#039) - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well. TCF4 is known to produce multiple transcripts; however as the complete structure is only known for the transcript that encodes the b isoform, that is the variant presented here.

Gene Name: transcription factor 4
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: TCF4, BHLHb19, E2-2, ITF-2, ITF2, PTHS, SEF2-1B, SEF2-1, SEF2-1A, SL3-3 enhancer factor 2, SEF2, SEF-2, TCF-4, Transcription factor 4
Target Sequences: NM_003199 NP_003190.1 P15884

Publications (2)

1
Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy. Afshari NA, Igo RP Jr, Morris NJ, Stambolian D, Sharma S, Pulagam VL, Dunn S, Stamler JF, Truitt BJ, Rimmler J, Kuot A, Croasdale CR, Qin X, Burdon KP, Riazuddin SA, Mills R, Klebe S, Minear MA, Zhao J, Balajonda E, Rosenwasser GO, Baratz KH, Mootha VV, Patel SV, Gregory SG, Bailey-Wilson JE, Price MO, Price FW Jr, Craig JE, Fingert JH, Gottsch JD, Aldave AJ, Klintworth GK, Lass JH, Li YJ, Iyengar SK. Nature communications. 2017 8:14898. (IHC; Human) [Full Text Article] [PubMed:28358029] [PMC:PMC5379100] Related Antibodies: LS-B1570.
2
Primary fibroblasts of NDUFS4(-/-) mice display increased ROS levels and aberrant mitochondrial morphology. Valsecchi F, Grefte S, Roestenberg P, Joosten-Wagenaars J, Smeitink JA, Willems PH, Koopman WJ. Mitochondrion. 2013 Sep;13:436-43. [Full Text Article] [PubMed:23234723] Related Antibodies: LS-B1570.

☰ Filters
Antibodies (42)
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Over-Expression Lysate (4)
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TCF4 (57)
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rabbit (37)
mouse (5)
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monoclonal mc (5)
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TCF4 Antibody - Anti-TCF4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (aa73-122) LS-B1570
(4.1) Rating
(2) Publication(s)
TCF4 Rabbit anti-Human Polyclonal (aa73-122) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$375
TCF4 Antibody - Anti-TCF4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (aa73-122, HRP) LS-C481861
TCF4 Rabbit anti-Human Polyclonal (aa73-122) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
TCF4 Antibody - Anti-TCF4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (aa73-122, Biotin) LS-C481859
TCF4 Rabbit anti-Human Polyclonal (aa73-122) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
TCF4 Antibody - Anti-TCF4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (aa73-122, FITC) LS-C481860
TCF4 Rabbit anti-Human Polyclonal (aa73-122) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
TCF4 Antibody - Immunofluorescence analysis of HeLa cell using TCF4 antibody. Blue: DAPI for nuclear staining.
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TCF4 Antibody LS-C331289
TCF4 Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
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TCF4 Antibody (aa48-73, APC) LS-C271204
TCF4 Rabbit anti-Human Polyclonal (aa48-73) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
TCF4 Antibody - Human, Thymus: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (N-Terminus) LS-B8267
TCF4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$375
TCF4 Antibody - Human, Thymus: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (N-Terminus, HRP) LS-C481857
TCF4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Guinea pig, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
TCF4 Antibody - Human, Thymus: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (N-Terminus, Biotin) LS-C481856
TCF4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Guinea pig, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
TCF4 Antibody - Human, Thymus: Formalin-Fixed Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TCF4 Antibody (N-Terminus, FITC) LS-C481858
TCF4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Guinea pig, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
TCF4 Antibody - TCF4 Antibody western blot of K562 cell line lysates (35 ug/lane). The TCF4 antibody detected the TCF4 protein (arrow).
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TCF4 Antibody (aa48-73) LS-C161772
TCF4 Rabbit anti-Human Polyclonal (aa48-73) Antibody
Human
WB
Unconjugated
400 µl/$393
TCF4 Antibody - Immunofluorescent analysis of TCF4 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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TCF4 Antibody LS-C482261
TCF4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386
TCF4 Antibody - Western blot of TCF4 pAb in extracts from K562 cells.
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TCF4 Antibody LS-C192392
TCF4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
TCF4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF4 Polyclonal Antibody. Tissue: Kidney. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF4 Polyclonal Antibody at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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TCF4 Antibody (FITC) LS-C775081
TCF4 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
IHC, WB
FITC Conjugated
100 µg/$472
TCF4 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution of 1:100
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TCF4 Antibody LS-C679751
TCF4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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TCF4 Antibody LS-C660935
TCF4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
TCF4 Protein
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Human TCF4 Protein (Recombinant His) - LS-G2817
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
TCF4 Antibody - Immunofluorescence of monoclonal antibody to TCF4 on HeLa cell. [antibody concentration 10 ug/ml]
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TCF4 Antibody (clone 3E10) LS-C198312
TCF4 Mouse anti-Human Monoclonal (3E10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$335
TCF4 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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TCF4 Antibody LS-C805474
TCF4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
TCF4 Antibody - Immunofluorescence staining of TCF4 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TCF4 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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TCF4 Antibody LS-C817430
TCF4 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$302
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TCF4 Antibody (clone 7B1B3) LS-C669563
TCF4 Mouse anti-Human Monoclonal (7B1B3) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
TCF4 Antibody - Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using TCF4 antibody (clone TCF4/1705). These results demonstrate the foremost specificity of the TCF4/1705 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
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TCF4 Antibody (clone TCF4/1705, Azide-free, BSA-free) LS-C782455
TCF4 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (TCF4/1705) Antibody
Human
ELISA, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
TCF4 Antibody - Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using TCF4 antibody (clone TCF4/1705). These results demonstrate the foremost specificity of the TCF4/1705 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Select
TCF4 Antibody (clone TCF4/1705) LS-C782457
TCF4 Mouse anti-Human Monoclonal (TCF4/1705) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$371; 100 µg/$574
TCF4 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TCF4 Antibody LS-C806071
TCF4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
TCF4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF4 Polyclonal Antibody. Tissue: Kidney. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF4 Polyclonal Antibody at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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TCF4 Antibody LS-C775077
TCF4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µg/$442
Viewing 1-25 of 57 product results



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