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TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.
Gene Name: | transcription elongation factor A (SII)-like 1 |
Synonyms: | TCEAL1, TCEA-like protein 1, p21, Pp21, SIIR |
Target Sequences: | NM_004780 NP_004771.2 Q15170 |
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