Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
Gene Name: | titin-cap |
Synonyms: | TCAP, 19 kDa sarcomeric protein, CMD1N, LGMD2G, TELE, Titin cap protein, Titin-cap, Titin-cap (telethonin), T-cap, Telethonin |
Target Sequences: | NM_003673 NP_003664.1 O15273 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.