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TC21 / RRAS2 is a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.
Gene Name: | related RAS viral (r-ras) oncogene homolog 2 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | RRAS2, Ras-like protein TC21, Ras-related protein R-Ras2, TC21, Teratocarcinoma oncogene |
Target Sequences: | NM_012250 NP_036382.2 P62070 |
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