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TBX10 is a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate.
Gene Name: | T-box 10 |
Synonyms: | TBX10, T-box 10, TBX13, TBX7, T-box protein 10, T-box 7 |
Target Sequences: | NM_005995 NP_005986.2 O75333 |
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