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N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
Gene Name: | N-myristoyltransferase 2 |
Synonyms: | NMT2, NMT 2, Type II N-myristoyltransferase, N-myristoyltransferase 2 |
Target Sequences: | NM_004808 NP_004799.1 O60551 |
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