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POP1 is the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.
Gene Name: | Processing Of Precursor 1, Ribonuclease P/MRP Subunit (S. Cerevisiae) |
Synonyms: | POP1, HPOP1, KIAA0061, Processing of precursors 1 |
Target Sequences: | D31765 BAA06543.1 Q99575 |
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