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LIV-1/Slc39A6 belongs to the LZT (LIV-1 subfamily of ZIP zinc transporters) subfamily of zinc transporters. These proteins control the levels of zinc in cells, which is an essential ion for cells that plays a role in controlling the cellular processes of the cell, such as growth, development and differentiation. Originally isolated from breast carcinoma, high levels of LIV-1 have been associated with better outcomes for breast carcinoma patients.
Gene Name: | solute carrier family 39 (zinc transporter), member 6 |
Family/Subfamily: | Transporter , Zinc-iron transporter |
Synonyms: | SLC39A6, LIV1, LIV-1, ZIP-6, Zrt- and Irt-like protein 6, Zinc transporter ZIP6, ZIP6 |
Target Sequences: | NM_012319 NP_036451.3 Q13433 |
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