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Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
Gene Name: | branched chain ketoacid dehydrogenase kinase |
Family/Subfamily: | Protein Kinase , PDK/BCKDK |
Synonyms: | BCKDK, BCKDKD, BCKDH kinase, BCKDHKIN, BCODC kinase, BCODH kinase, BCKA dehydrogenase kinase, BCKAD kinase, BCKD-kinase, BDK |
Target Sequences: | NM_005881 NP_005872.2 O14874 |
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