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Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
Gene Name: | glycine-N-acyltransferase |
Synonyms: | GLYAT, AAc, ACGNAT, Aralkyl-CoA N-acyltransferase, Glycine N-benzoyltransferase, Glycine-N-acyltransferase, GAT, Glycine N-acyltransferase, HRP-1(CLP) |
Target Sequences: | NM_005838 NP_005829.3 Q6IB77 |
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