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The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene.
Gene Name: | leukocyte-associated immunoglobulin-like receptor 2 |
Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
Synonyms: | LAIR2, CD306, CD306 antigen, LAIR-2 |
Target Sequences: | NM_002288 NP_002279.2 Q6ISS4 |
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