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ABLIM1 is a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: | actin binding LIM protein 1 |
Synonyms: | ABLIM1, ABLIM, Actin binding LIM protein 1, AbLIM-1, Actin-binding LIM protein 1, KIAA0059, LIMATIN, LIMAB1 |
Target Sequences: | NM_002313 NP_002304.3 O14639 |
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