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Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
Gene Name: | adiponectin receptor 2 |
Synonyms: | ADIPOR2, ACDCR2, Adiponectin receptor protein 2, Adiponectin receptor 2, PAQR2 |
Target Sequences: | NM_024551 NP_078827.2 Q86V24 |
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