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Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
Gene Name: | ubiquitin specific peptidase 11 |
Family/Subfamily: | Protease , Cysteine C19 |
Synonyms: | USP11, Deubiquitinating enzyme 11, Ubiquitin specific protease 11, Ubiquitin thiolesterase 11, Ubiquitin thioesterase 11, UHX1 |
Target Sequences: | NM_004651 NP_004642.2 P51784 |
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