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TESK1 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.
Gene Name: | testis-specific kinase 1 |
Family/Subfamily: | Protein Kinase , TESK |
Synonyms: | TESK1, Testicular protein kinase 1, Testis-specific kinase 1 |
Target Sequences: | NM_006285 NP_006276.2 Q15569 |
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