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SRI / Sorcin is a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
Gene Name: | sorcin |
Synonyms: | SRI, 22 kDa protein, CP22, CP-22, H_RG167B05.1, SCN, V19, Sorcin |
Target Sequences: | NM_003130 NP_003121.1 P30626 |
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