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SCG2 / Secretogranin II is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Gene Name: | secretogranin II |
Synonyms: | SCG2, Chromogranin-C, CHGC, EM66, Secretogranin II, Secretoneurin, SN, Secretogranin-2, SGII |
Target Sequences: | NM_003469 NP_003460.2 P13521 |
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