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Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens By similarity. Binds bacterial lipopolysaccharide (LPS).
Gene Name: | spondin 2, extracellular matrix protein |
Synonyms: | SPON2, DIL-1, DIL1, M-SPONDIN, Spondin-2, MINDIN |
Target Sequences: | NM_012445 NP_036577.1 Q9BUD6 |
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