Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
ACTR1A / Centractin is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Gene Name: | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
Synonyms: | ACTR1A, ARP1, CTRN1, Actin-RPV, Alpha-centractin, Centractin |
Target Sequences: | NM_005736 NP_005727.1 P61163 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.