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Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
Gene Name: | poly(A) polymerase alpha |
Synonyms: | PAPOLA, PAP, Poly(a) polymerase, PAP-alpha, Poly(A) polymerase alpha |
Target Sequences: | NM_032632 NP_116021.2 P51003 |
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