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LRRC8A / LRRC8
leucine rich repeat containing 8 family, member A
Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity. Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development.
| Gene Name: | leucine rich repeat containing 8 family, member A |
| Synonyms: | LRRC8A, AGM5, LRRC8, KIAA1437 |
| Target Sequences: | AB037858 BAA92675.1 Q8IWT6 |
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Antibodies
(18)
Proteins
(10)
Type
Over-Expression Lysate
(6)
Primary
(18)
Recombinant
(4)
Target
LRRC8A / LRRC8
(28)
Reactivity
Human
(18)
Mouse
(5)
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(4)
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(6)
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(6)
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(3)
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(6)
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(6)
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(6)
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(6)
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(3)
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(6)
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(6)
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(3)
Xenopus
(3)
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(3)
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IHC
(2)
IHC-P
(2)
WB
(18)
ELISA
(8)
IP
(1)
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rabbit
(18)
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IHCPlus
(2)
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IgG
(16)
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polyclonal pc
(18)
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(1)
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(3)
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(3)
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(3)
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(1)
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(7)
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aa782-810
(7)
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(4)
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(4)
aa648-803
(1)
aa760-810
(1)
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No
(28)
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GST, N-terminus
(1)
Myc-DDK (Flag)
(9)
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(7)
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293T Cells
(3)
HEK 293 Cells
(6)
Wheat Germ Extract
(1)
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa648-803) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa760-810) Antibody
Mouse, Human
IHC-P, IP, WB
Unconjugated
50 µl/$460
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
LRRC8A / LRRC8 Rabbit anti-Human Polyclonal (aa782-810) Antibody
Human
WB
Unconjugated
400 µl/$393
HEK 293 Cells
Myc-DDK (Flag)
94 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
94 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
94 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
94 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
94 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
94 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
94 kDa
20 µg/$150
Viewing 1-25
of 28
product results
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