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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein.
Gene Name: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 |
Family/Subfamily: | DEAD box protein |
Synonyms: | DDX18, DEAD box protein 18, Myc-regulated DEAD box protein, MrDb |
Target Sequences: | NM_006773 NP_006764.3 Q9NVP1 |
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