NGFRAP1 / NADE / Bex

nerve growth factor receptor (TNFRSF16) associated protein 1

The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization. It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed. Finally, although initially discovered as an mRNA expressed in ovarian granulosa cells, NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage.

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Products

Antibodies (14)

Proteins (7)

Type

Over-Expression Lysate (4)

Primary (14)

Recombinant (3)

Target

NGFRAP1 / NADE / Bex (21)

Reactivity

Human (14)

Mouse (4)

Rat (1)

Application

IHC (3)

IHC-P (2)

WB (13)

ELISA (10)

IF (2)

Host

rabbit (14)

Product Group

IHCPlus (1)

Isotype

IgG (12)

Clonality

polyclonal pc (14)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa14-42 (7)

Internal (1)

Publications

No (21)

Tag

GST (2)

His (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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IHC-plus™ NGFRAP1 / NADE / Bex Antibody LS-B532

(4.0) Rating

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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NGFRAP1 / NADE / Bex Antibody LS-C346340

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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NGFRAP1 / NADE / Bex Antibody LS-C675420

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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NGFRAP1 / NADE / Bex Antibody LS-C764869

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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NGFRAP1 / NADE / Bex Antibody (aa14-42) LS-C329892

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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NGFRAP1 / NADE / Bex Antibody (aa14-42, Biotin) LS-C264343

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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NGFRAP1 / NADE / Bex Antibody (aa14-42, FITC) LS-C264344

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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NGFRAP1 / NADE / Bex Antibody (aa14-42, APC) LS-C264341

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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NGFRAP1 / NADE / Bex Antibody (aa14-42, Azide-free, HRP) LS-C264346

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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NGFRAP1 / NADE / Bex Antibody (aa14-42, PE) LS-C264347

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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NGFRAP1 / NADE / Bex Antibody LS-C667159

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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NGFRAP1 / NADE / Bex Antibody LS-C779098

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$357

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NGFRAP1 / NADE / Bex Antibody (Internal) LS-C16680

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$649

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NGFRAP1 / NADE / Bex Antibody (aa14-42) LS-C158384

Antibody:

NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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Human NGFRAP1 / NADE / Bex Protein (Recombinant GST) (Full Length) - LS-G21005

Source:

E. coli

Tag:

GST

Molecular Weight:

40.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NGFRAP1 / NADE / Bex Protein (Recombinant His) (Full Length) - LS-G23055

Source:

Yeast

Tag:

His

Molecular Weight:

15 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human NGFRAP1 / NADE / Bex Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77848

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

20 µg/$150

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Human NGFRAP1 / NADE / Bex Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77850

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

20 µg/$150

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NGFRAP1 / NADE / Bex Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102946

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

100 µg/$494

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Human NGFRAP1 / NADE / Bex Protein (Recombinant GST) (Full Length) - LS-G33232

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.2 kDa

Price:

10 µg/$479; 25 µg/$670

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NGFRAP1 / NADE / Bex Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113989

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

100 µg/$494

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