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The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 [PubMed 9099850]).
Gene Name: | NME/NM23 nucleoside diphosphate kinase 4 |
Synonyms: | NME4, NM23D, NDP kinase, mitochondrial, NDPK-D, NM23H4, NDK, NDP kinase D, NDPKD, Nm23-H4 |
Target Sequences: | NM_005009 NP_005000.1 O00746 |
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