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Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.
Gene Name: | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
Synonyms: | GNAI2, H_LUCA16.1, GNAI2B, H_LUCA15.1 |
Target Sequences: | NM_002070 NP_002061.1 P04899 |
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