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TRIM54 / MURF contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene Name: | tripartite motif containing 54 |
Family/Subfamily: | Tripartite Motif |
Synonyms: | TRIM54, MURF, MURF-3, MuRF3, RING finger protein 30, Tripartite motif-containing 54, RNF30, Tripartite motif containing 54 |
Target Sequences: | NM_032546 NP_115935.3 Q9BYV2 |
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