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Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
Gene Name: | increased sodium tolerance 1 homolog (yeast) |
Synonyms: | IST1, CRS1, HIST1, IST1 homolog, KIAA0174, OLC1, Increased sodium tolerance-1, SCS, Overexpressed in lung cancer 1, TWACS3 |
Target Sequences: | NM_014761 NP_055576.2 P53990 |
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