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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Gene Name: | snurportin 1 |
Synonyms: | SNUPN, KPNBL, RNA U transporter 1, RNA, U transporter 1, Snurportin 1, Snurportin1, Snurportin-1, SPN1, RNUT1 |
Target Sequences: | NM_005701 NP_005692.1 O95149 |
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