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Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Gene Name: | src kinase associated phosphoprotein 1 |
Synonyms: | SKAP1, Pp55, SKAP55, SKAP-55, SCAP1 |
Target Sequences: | NM_003726 Q86WV1 Q86WV1 |
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