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HGFAC / HGFA is a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.
Gene Name: | HGF activator |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | HGFAC, HGF activator, HGFA, HGFAP |
Target Sequences: | NM_001528 NP_001519.1 Q04756 |
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