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The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'
Gene Name: | hemoglobin, epsilon 1 |
Synonyms: | HBE1, Epsilon globin, Epsilon-globin, Hemoglobin epsilon chain, HBE, Hemoglobin, epsilon 1, Hemoglobin epsilon, Hemoglobin subunit epsilon |
Target Sequences: | NM_005330 NP_005321.1 P02100 |
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