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KRT78 / Keratin 78 is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.
Gene Name: | keratin 78 |
Synonyms: | KRT78, CK-78, Cytokeratin-78, Kb40, Keratin 5b, Keratin-78, K5B, Keratin 78, Keratin-5b, Type-II keratin Kb40, K78 |
Target Sequences: | NM_173352 NP_775487.2 Q8N1N4 |
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