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May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
Gene Name: | TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
Synonyms: | TIPRL, Type 2A-interacting protein, DJ69E11.3, RP1-69E11.1, TIP, TIP41, TIP41-like protein |
Target Sequences: | NP_690866.1 O75663 |
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