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May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
Gene Name: | NFAT activating protein with ITAM motif 1 |
Synonyms: | NFAM1, BK126B4.4, CNAIP, NFAT activation molecule 1 |
Target Sequences: | Q8NET5 Q8NET5 |
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