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DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
Gene Name: | chromodomain helicase DNA binding protein 1-like |
Synonyms: | CHD1L, Amplified in liver cancer 1, CHDL, ALC1 |
Target Sequences: | NM_004284 NP_004275.4 Q86WJ1 |
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