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APOL3 / Apolipoprotein L 3 is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants.
Gene Name: | apolipoprotein L, 3 |
Synonyms: | APOL3, ApoL-III, Apolipoprotein L3, APOLIII, CG12_1, CG12-1, CG121, TNF-inducible protein CG12-1, Apolipoprotein L, 3, Apolipoprotein L-III |
Target Sequences: | NM_014349 NP_055164.1 O95236 |
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