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SGMS1 / TMEM23
sphingomyelin synthase 1
Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
| Gene Name: | sphingomyelin synthase 1 |
| Synonyms: | SGMS1, Hmob33, MOB, MOB1, Sphingomyelin synthase 1, TMEM23, Transmembrane protein 23, Protein Mob, SMS1 |
| Target Sequences: | NM_147156 NP_671512.1 Q86VZ5 |
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Antibodies
(25)
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(3)
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Over-Expression Lysate
(2)
Primary
(25)
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Target
SGMS1 / TMEM23
(28)
Reactivity
Human
(24)
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(10)
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(7)
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(6)
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(6)
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(6)
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(6)
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(22)
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rabbit
(25)
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(18)
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(25)
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(1)
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(1)
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(4)
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(4)
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(4)
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(1)
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(11)
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aa24-53
(7)
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(4)
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(4)
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(28)
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Purified
(1)
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$466
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$572
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa144-193) Antibody
Human
WB
Unconjugated
100 µl/$424
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa144-193) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (aa24-53) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$294; 100 µg/$360
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
SGMS1 / TMEM23 Rabbit anti-Mouse Polyclonal (aa154-203) Antibody
Mouse
WB
Unconjugated
100 µl/$424
SGMS1 / TMEM23 Rabbit anti-Mouse Polyclonal (aa154-203) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Mouse Polyclonal (aa154-203) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Mouse Polyclonal (aa154-203) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SGMS1 / TMEM23 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25
of 28
product results
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