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Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
Gene Name: | chromosome 11 open reading frame 30 |
Synonyms: | C11orf30, EMSY, Protein EMSY, GL002 |
Target Sequences: | NM_020193 NP_064578.2 Q7Z589 |
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