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Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).
Gene Name: | chemokine (C-X-C motif) ligand 6 |
Family/Subfamily: | Intercrine , Intercrine alpha |
Synonyms: | CXCL6, Chemokine alpha 3, GCP-2, GCP2, SCYB6, C-X-C motif chemokine 6, CKA-3, Small-inducible cytokine B6 |
Target Sequences: | NM_002993 NP_002984.1 P80162 |
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