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Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
Gene Name: | negative elongation factor complex member C/D |
Synonyms: | NELFCD, NELF-C, TH1 drosophila homolog, TH1-like protein, TH1L, TH1-like (Drosophila), Negative elongation factor C/D, NELF-C/D, NELF-D, NELFD, HSPC130, TH1, TH1-like (Drosophila homolog), Trihydrophobin 1 |
Target Sequences: | AJ238742 NP_945327.2 Q922L6 |
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